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Fig. 2 | Skeletal Muscle

Fig. 2

From: Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of the skeletal muscle

Fig. 2

Single-cell RNA sequencing of young and old mononuclear cells from 7 DPI-injured muscle. A Experimental outline: mononuclear cells from hindlimb muscle from young (< 4 months old, n = 3) and old (> 20 months old, n = 3) male mice injured with CTX, collected at 7 DPI, and processed for scRNA-seq using the 10 × chromium platform. B UMAP of cells clustered together and separated based on young (left panel) and old (right panel) samples. C UMAP and clustering results of cells combined from both young and old mice. Colored based on clusters identified. D Violin plots for selected top marker genes used to label each cluster

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