Fig. 5

Relationship between EIM reactance and histopathological parameters in the GC muscle at 6–24 weeks of age in WT (black circle, n = 23) and mdx (red triangle, n = 23) mice. EIM data were obtained before muscle sampling at each time point. Correlations between 50 kHz EIM reactance and averaged muscle fiber CSA (A), the small muscle fiber population (CSA < 500 μm²) (B), or SR positive fibrosis area (C) were analyzed. Data were assessed using the Pearson’s correlation coefficient. EIM: electrical impedance myography, GC: gastrocnemius, WT: wild-type, CSA: cross-sectional area, SR: Sirius red