Table 1 Comparison of the baseline characteristics between patients with and without increase in ASM/W*

Demographic

 Age(years)

41.1±14.4

40.9±15.1

41.4±12.9

0.79

 Male, n (%)

182 (71.1)

121 (72.0)

61 (69.3)

0.65

 Smoke

39 (15.2)

25 (14.8)

14 (15.9)

0.83

 Alcohol consumption

27 (10.5)

17 (10.1)

10 (11.4)

0.76

Anthropometric

 Weight (kg)

74.1±13.7

74.4±13.3

73.5±14.5

0.61

 BMI (kg/m²)

26.7±3.9

26.8±3.6

26.5±4.3

0.58

 WC (cm)

91.9±9.5

91.6±9.2

92.5±10.2

0.48

 Diastolic blood pressure (mmHg)

129±17

129±17

129±16

0.93

 Systolic blood pressure (mmHg)

85±12

85±12

85±13

0.70

Liver biochemistry

 ALT (U/L)

45(29, 75)

53(31, 83)

37(21, 55)

<0.001

 AST (U/L)

34(23, 46)

37(26, 51)

28(21, 38)

<0.001

 GGT (U/L)

43(28, 72)

48(32, 78)

33(24, 50)

<0.001

 ALP (U/L)

77(66, 88)

78(67, 89)

74(64, 85)

0.08

Metabolic characteristics

 TC (mmol/L)

5.0±1.0

5.0±1.0

5.0±0.8

0.71

 TG (mmol/L)

1.5(1.2, 2.2)

1.6(1.2, 2.4)

1.4(1.2, 2.1)

0.22

 HDL-C (mmol/L)

1.1±0.2

1.1±0.3

1.1±0.2

0.81

 LDL-C (mmol/L)

3.1±0.7

3.1±0.8

3.1±0.7

0.78

 FSG (mmol/L)

5.2±1.3

5.2±1.4

5.2±1.1

0.74

 HOMA-IR

2.5(1.6, 3.8)

2.7(1.7, 4.1)

2.2(1.5, 3.4)

0.10

 Uric acid (μmol/L)

430±110

426±109

439±110

0.38

Metabolic syndrome

87 (33.9)

54 (32.1)

33 (37.5)

0.39

Liver stiffness (kPa)

5.9(5.3, 6.8)

5.9(5.3, 7.1)

5.9(5.4, 6.6)

0.88

LFC (%)

14.9(9.6, 22.4)

17.1(11.2, 24.8)

11.5(7.7, 18.9)

<0.001

Body composition

 ASM (kg)

23.8±5.6

23.9±5.6

23.8±5.6

0.85

 ASM/W (%)

32.0±4.1

31.8±4.0

32.3±4.3

0.37

 Body muscle mass (kg)

25.9±3.9

26.0±3.9

25.7±4.1

0.68

 Total fat mass (kg)

21.0±8.8

20.7±7.7

21.7±10.5

0.40

Interventions

0.64

 Orlistat

16 (6.3)

8 (4.8)

8 (9.1)

 Meal replacement

10 (3.9)

4 (2.4)

6 (6.8)

 Lifestyle

230 (89.8)

154 (91.7)

76 (86.4)

Drugs

 Statin, n (%)

66 (25.8)

41 (24.4)

25 (28.4)

0.23

 Antidiabetic, n (%)

24 (9.3)

13 (7.7)

11 (12.5)

0.21