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Fig. 2 | Skeletal Muscle

Fig. 2

From: IL-33-ST2 signaling in fibro-adipogenic progenitors alleviates immobilization-induced muscle atrophy in mice

Fig. 2

Expression of Il33 and Il1rl1 transcripts in FAPs is induced after immobilization. A Number of genes expressed in FAPs that showed > twofold or < 0.5-fold changes from the baseline controls on days 3 and 14 of hindlimb immobilization in young and aged mice. B Top 10 DEGs that showed the greatest increase from the baseline controls on days 3 and 14 of hindlimb immobilization in young and aged mice. C Transcript per million values of Il33 in FAPs of young and aged mice on days 0, 3, and 14 of immobilization (n = 2). D Expression levels of Il33 (left) and Il1rl1 (right) transcripts in the TA muscles from young and aged mice on days 0, 3, and 14 of immobilization (n = 3–5). *P < 0.05; **P < 0.01

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